Document Detail

Investigation of the arterial stiffness on renal artery Doppler sonograms.
MedLine Citation:
PMID:  19397094     Owner:  NLM     Status:  MEDLINE    
This study aims to identify the effect of stiffness on renal artery Doppler sonograms by using a curve fitting approach. The study includes 20 patients with suspected renovascular hypertension. Each patient underwent recordings during renal artery examinations before and after administration of Captopril 25 mg (Kapril tablet, MN Pharmaceuticals, Istanbul, Turkey). Doppler signals were analyzed with short time Fourier transformation, followed by curve fitting to sonograms using Savitzky-Golay method. Doppler parameters obtained from pre- and post-Captopril curve-fitted sonograms were statistically compared with "Paired-Samples t-Test". Captopril administration resulted in a significant decrease in the mean frequency and a significant increase in Pulsatility Index of the periods. No significant difference was detected between maximum systolic and minimum diastolic frequencies, Resistivity Index, and the Acceleration Index. The computational approach in this study appears to be promising.
Mahmut Tokmakçi; Nuri Erdoğan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of medical systems     Volume:  33     ISSN:  0148-5598     ISO Abbreviation:  J Med Syst     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-04-28     Completed Date:  2009-06-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7806056     Medline TA:  J Med Syst     Country:  United States    
Other Details:
Languages:  eng     Pagination:  101-6     Citation Subset:  IM    
Department of Biomedical Engineering, Engineering Faculty, Erciyes University, 38039 Kayseri, Turkey.
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MeSH Terms
Antihypertensive Agents / administration & dosage,  diagnostic use
Captopril / administration & dosage,  diagnostic use
Data Interpretation, Statistical
Fourier Analysis
Hypertension, Renovascular / physiopathology,  ultrasonography*
Image Processing, Computer-Assisted / methods*
Middle Aged
Pulsatile Flow
Renal Artery / drug effects,  physiopathology,  ultrasonography*
Renal Artery Obstruction / physiopathology,  ultrasonography*
Ultrasonography, Doppler / methods*
Vascular Resistance
Reg. No./Substance:
0/Antihypertensive Agents; 62571-86-2/Captopril

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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