Document Detail


Investigation and Treatment of a Complicated Inflammatory Aortoiliac Aneurysm.
MedLine Citation:
PMID:  22308209     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Inflammatory abdominal aortic aneurysms (IAAAs) account for 5% to 10% of all abdominal aortic aneurysms, occurring primarily in males. Their true etiology is unknown. Symptoms and signs of IAAA are so variable that they present to a wide range of specialties. There is debate in the literature whether IAAA is a manifestation of systemic autoimmune disease. We describe the case of a young female patient with complicated inflammatory aortoiliac aneurysmal disease, illustrating diagnostic and treatment challenges that remain. Our patient had a positive autoantibody screen, raised erythrocyte sedimentation rate, positive enzyme-linked immunosorbent spot test, and saccular aneurysms, including infective and inflammatory etiologies in her differential diagnosis. Early diagnosis is crucial to limit disease progression, morbidity, and mortality. Medical management is important to address the underlying disease process, but a combination of endovascular and open surgical intervention is often necessary for definitive treatment. Available evidence offers plausibility for benefit of endovascular intervention over open repair.
Authors:
Maresa A Brake; Joseph Shalhoub; Jeremy S Crane; Richard G J Gibbs; Ian J Franklin
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-5
Journal Detail:
Title:  Vascular and endovascular surgery     Volume:  -     ISSN:  1938-9116     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136421     Medline TA:  Vasc Endovascular Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Imperial Vascular Unit, Imperial College Healthcare NHS Trust, London, UK.
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