| Investigation of the Association between Helicobacter pylori Infection and Normal Tension Glaucoma. | |
| | |
MedLine Citation:
|
PMID: 20811063 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Purpose. To investigate whether Helicobacter pylori infection is associated with normal tension glaucoma (NTG). Methods. One hundred consecutive NTG patients (group 1) from an outpatient glaucoma clinic were enrolled. Medical records of the 88 control participants (control 1) of the outpatient clinic, and 104 NTG patients (group 2) and 1116 healthy controls (control 2) (1220 subjects in total) from a primary health care center were reviewed retrospectively to compare the RESULTS: Serum samples from all subjects were analyzed for the presence of H. pylori-specific immunoglobulin G antibodies using ELISA. The distributions of serologic H. pylori test results of the NTG patients and control subjects were compared, and possible associations between clinical phenotypes and positive serologic results were assessed. Bilaterality of NTG patients was also analyzed. Results. NTG patients had significantly more positive serologic results than did the healthy controls. There were significant differences between group 1 and control 1 patients (P = 0.020; odds ratio [OR], 2.05), group 1 and control 2 patients (P = 0.016; OR, 1.73), and group 2 and control 2 patients (P = 0.008; OR, 1.83). However, no significant association was found between clinical characteristics and a positive serologic result for H. pylori in NTG patients. Conclusions. This study suggests that H. pylori infection may be associated with an increased risk for NTG. H. pylori may play a role in the development or progression of NTG as a secondary aggravating factor because of the coexistence of other main causes or it may be the primary cause. |
| | |
Authors:
|
Joon Mo Kim; Seok Hwan Kim; Ki Ho Park; So Young Han; Hyoung Sub Shim |
Related Documents
:
|
3261993 - Alpha 1-antitrypsin phenotypes in acute anterior uveitis. 8341503 - Intraocular lens implantation versus no intraocular lens implantation in patients with ... 6668473 - Ambulatory electrocardiographic recording in mild or moderate myotonic dystrophy and my... |
Publication Detail:
|
Type: Journal Article Date: 2011-02-03 |
Journal Detail:
|
Title: Investigative ophthalmology & visual science Volume: 52 ISSN: 1552-5783 ISO Abbreviation: Invest. Ophthalmol. Vis. Sci. Publication Date: 2011 |
Date Detail:
|
Created Date: 2011-02-04 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7703701 Medline TA: Invest Ophthalmol Vis Sci Country: United States |
Other Details:
|
Languages: eng Pagination: 665-8 Citation Subset: IM |
Affiliation:
|
Department of Ophthalmology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Korea; |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Retinal ganglion cell loss in a rat ocular hypertension model is sectorial and involves early optic ...
Next Document: Age-severity relationships in families linked to FCD2 with retroillumination photography.