Document Detail


Investigating unstable fixation in patients with macular disease.
MedLine Citation:
PMID:  20926809     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To assess the effect on visual acuity of compensating fixation instability by controlling retinal image motion in people with macular disease.
METHODS: Ten patients with macular disease participated in this study. Crowded and noncrowded visual acuity were measured using an eye tracking system to compensate for fixation instability. Four conditions, corresponding to four levels of retinal image motion, were tested: no compensation (normal motion), partial compensation (reduced motion), total compensation (no motion), and overcompensation (increased motion). Fixation stability and the number of preferred retinal loci were also measured.
RESULTS: Modulating retinal image motion had the same effect on crowded and noncrowded visual acuity (P = 0.601). When fixation instability was overcompensated, acuity worsened by 0.1 logMAR units (P < 0.001) compared with baseline (no compensation) and remained equal to baseline for all other conditions.
CONCLUSIONS: In people with macular disease, retinal image motion caused by fixation instability does not reduce either crowded or noncrowded visual acuity. Acuity declines when fixation instability is overcompensated, showing limited tolerance to increased retinal image motion. The results provide evidence that fixation instability does not improve visual acuity and may be a consequence of poor oculomotor control.
Authors:
Antonio F Macedo; Michael D Crossland; Gary S Rubin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-03-10
Journal Detail:
Title:  Investigative ophthalmology & visual science     Volume:  52     ISSN:  1552-5783     ISO Abbreviation:  Invest. Ophthalmol. Vis. Sci.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-14     Completed Date:  2011-05-20     Revised Date:  2013-01-09    
Medline Journal Info:
Nlm Unique ID:  7703701     Medline TA:  Invest Ophthalmol Vis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1275-80     Citation Subset:  IM    
Affiliation:
Department of Visual Neuroscience, UCL Institute of Ophthalmology, London, United Kingdom. filipe3305@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Fixation, Ocular / physiology*
Humans
Macular Degeneration / physiopathology*
Middle Aged
Ocular Motility Disorders / physiopathology*
Retina / physiology
Vision, Binocular
Visual Acuity / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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