Document Detail

Investigating the changes in heart rate asymmetry (HRA) with perturbation of parasympathetic nervous system.
MedLine Citation:
PMID:  23250577     Owner:  NLM     Status:  Publisher    
The heart rate asymmetry (HRA) is a disproportionate distribution of heart rate signal. The current study was designed to assess the changes in HRA in experimental conditions using Poincaré plot during parasympathetic blockade (atropine infusion) and parasympathetic enhancement (scopolamine administration). After atropine infusion, the heart rate variability in 5 out of 8 subjects was found asymmetric. In contrast, all 8 subjects were found to be asymmetric during scopolamine administration. The physiological relevance of HRA was demonstrated by showing correlation with standard frequency domain parameters during all phases of the experiment. The deviation of asymmetry index (GI ( p )) from symmetric range was further analyzed, which was maximum during scopolamine administration and minimum during atropine infusion. These findings suggest that parasympathetic block reduces the prevalence of HRA, and has significant correlation of GI ( p ) with frequency domain features of HRV analysis.
Chandan Karmakar; Ahsan Khandoker; Marimuthu Palaniswami
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-19
Journal Detail:
Title:  Australasian physical & engineering sciences in medicine / supported by the Australasian College of Physical Scientists in Medicine and the Australasian Association of Physical Sciences in Medicine     Volume:  -     ISSN:  0158-9938     ISO Abbreviation:  Australas Phys Eng Sci Med     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8208130     Medline TA:  Australas Phys Eng Sci Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Electrical & Electronic Engineering, The University of Melbourne Parkville, Melbourne, VIC, 3010, Australia,
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