Document Detail


Investigating brain response to music: a comparison of different fMRI acquisition schemes.
MedLine Citation:
PMID:  20728550     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Functional magnetic resonance imaging (fMRI) in auditory experiments is a challenge, because the scanning procedure produces considerable noise that can interfere with the auditory paradigm. The noise might either mask the auditory material presented, or interfere with stimuli designed to evoke emotions because it sounds loud and rather unpleasant. Therefore, scanning paradigms that allow interleaved auditory stimulation and image acquisition appear to be advantageous. The sparse temporal sampling (STS) technique uses a very long repetition time in order to achieve a stimulus presentation in the absence of scanner noise. Although only relatively few volumes are acquired for the resulting data sets, there have been recent studies where this method has furthered remarkable results. A new development is the interleaved silent steady state (ISSS) technique. Compared with STS, this method is capable of acquiring several volumes in the time frame between the auditory trials (while the magnetization is kept in a steady state during stimulus presentation). In order to draw conclusions about the optimum fMRI procedure with auditory stimulation, different echo-planar imaging (EPI) acquisition schemes were compared: Continuous scanning, STS, and ISSS. The total acquisition time of each sequence was adjusted to about 12.5 min. The results indicate that the ISSS approach exhibits the highest sensitivity in detecting subtle activity in sub-cortical brain regions.
Authors:
Karsten Mueller; Toralf Mildner; Thomas Fritz; Jöran Lepsien; Christian Schwarzbauer; Matthias L Schroeter; Harald E Möller
Publication Detail:
Type:  Journal Article     Date:  2010-08-20
Journal Detail:
Title:  NeuroImage     Volume:  54     ISSN:  1095-9572     ISO Abbreviation:  Neuroimage     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-10-22     Completed Date:  2011-01-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9215515     Medline TA:  Neuroimage     Country:  United States    
Other Details:
Languages:  eng     Pagination:  337-43     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Inc. All rights reserved.
Affiliation:
Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany. karstenm@cbs.mpg.de
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MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation
Auditory Cortex / anatomy & histology,  physiology
Brain / anatomy & histology,  physiology*
Brain Mapping / methods*
Cognitive Dissonance
Functional Laterality
Hearing / physiology
Humans
Magnetic Resonance Imaging / methods*
Music*
Noise

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