Document Detail

Inverted papilloma of the nasal cavity presenting with massive amounts of squamous metaplastic cells in sputum. A case report.
MedLine Citation:
PMID:  12040661     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Squamous metaplasic cells are rarely seen in sputum of female nonsmokers. CASE: A 47-year-old female nonsmoker presented with massive amounts of squamous metaplasic cells in sputum and an elevated level of squamous cell carcinoma (SCC) antigen in serum present for months, while no causative lesion was detected either by lung computed tomography or bronchoscopy. The patient was eventually diagnosed as having inverted papilloma in the right nasal cavity. Resection of the tumor brought about disappearance of squamous metaplastic cells in sputum and return of serum SCC antigen to the normal range. CONCLUSION: This case clearly demonstrates that squamous metaplastic cells in sputum can originate in lesions in the nasal cavity, although they are rare. It should be kept in mind that the nasal cavity is a potential site producing squamous metaplastic cells in sputum.
Koichi Yamazaki; Yasushi Furuta; Katsuji Marukawa; Jun Moriya; Mikio Shimizu; Mikio Arakawa; Tomoo Itoh; Michio Shimizu; Shinichi Fukumoto; Shigeaki Ogura; Hirotoshi Dosaka-Akita; Masaharu Nishimura
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta cytologica     Volume:  46     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    2002 May-Jun
Date Detail:
Created Date:  2002-06-03     Completed Date:  2002-06-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  596-600     Citation Subset:  IM    
First Department of Medicine, Hokkaido University School of Medicine, North 15, West 7, Kita-ku, Sapporo 060-8638, Japan.
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MeSH Terms
Antigens, Neoplasm / blood
Cytodiagnosis / methods
Follow-Up Studies
Middle Aged
Nasal Cavity* / pathology
Nose Neoplasms / diagnosis,  pathology*
Papilloma, Inverted / diagnosis,  pathology*
Sputum / cytology*
Reg. No./Substance:
0/Antigens, Neoplasm; 0/Serpins; 0/squamous cell carcinoma-related antigen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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