Document Detail


Inverted ductal papilloma of minor salivary gland: case report with immunohistochemical study and literature review.
MedLine Citation:
PMID:  16872441     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Inverted ductal papilloma (IDP) is a type of ductal papilloma arising in ducts of minor salivary glands. Very few cases, and no cases in Japan, have been reported. Reported herein is a case of IDP with a review of the literature. The patient was a 49-year-old man presenting with a lump in the right buccal mucosa of the premolar area of the mandible. The tumor was excised en bloc after a biopsy diagnosis of IDP. On the surface of the covering epithelium, an opening was seen to be filled with mucinous material. On cut surface the opening led to the tumor cavity. The major portion of the tumor parenchyma was made up of papillary proliferation of basaloid squamous cells. Some crypts, microcysts, and mucous cells were seen. There were no findings suggestive of a malignant tumor. The patient's postoperative course was uneventful and there has been no recurrence after 1 year's follow up. Immunohistochemical analysis of the present case supports the hypothesis that IDP originates from squamous metaplasia and proliferation of minor salivary gland duct cells.
Authors:
Nobuhisa Kubota; Kenji Suzuki; Yoshiaki Kawai; Hideyuki Mizunuma; Ushaku Lee; Hiroaki Konishi; Hiroyuki Miyazaki; Eiro Kubota; Yoshihisa Watanabe
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pathology international     Volume:  56     ISSN:  1320-5463     ISO Abbreviation:  Pathol. Int.     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-28     Completed Date:  2006-09-14     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9431380     Medline TA:  Pathol Int     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  457-61     Citation Subset:  IM    
Affiliation:
Department of Diagnostic Pathology, Kanagawa Dental College Hospital, Yokosuka, Japan. nobunobu@kdcnet.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Humans
Keratins / analysis
Male
Middle Aged
Mouth Mucosa / chemistry,  pathology
Mucin-1 / analysis
Papilloma, Inverted / chemistry,  pathology*,  surgery
Salivary Ducts / chemistry,  pathology*,  surgery
Salivary Gland Neoplasms / chemistry,  pathology*,  surgery
Salivary Glands, Minor / chemistry,  pathology*,  surgery
Tumor Markers, Biological / analysis
Chemical
Reg. No./Substance:
0/Mucin-1; 0/Tumor Markers, Biological; 68238-35-7/Keratins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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