| Inversion and crossover recombination contributions to the spacing between two functionally linked genes. | |
| | |
MedLine Citation:
|
PMID: 22664801 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The roles of inversion and crossover recombination in determining the spacing between two functionally linked genes on an individual strand of DNA and the resulting genetic organization throughout the population is not well understood. We employ a computer simulation to look at the spacing between functionally linked genes after many generations of a population of haploid individuals, each with a single chromosome. Simulations show that inversion and crossover recombination combine to create four attractors in gene spacing. The two major attractors include one in which the linked genes are forced to be near each other and one in which the linked genes are forced to be separated by one third of the chromosome length. Multiplicative functional linkage between two linked genes also causes a decreased average spacing compared to additive and random functional linkage. |
| | |
Authors:
|
B K Clark; K J Wabick; J G Weidner |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-6-1 |
Journal Detail:
|
Title: Bio Systems Volume: - ISSN: 1872-8324 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
|
Created Date: 2012-6-5 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0430773 Medline TA: Biosystems Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012. Published by Elsevier Ireland Ltd. |
Affiliation:
|
Department of Physics, Illinois State University, Normal, IL 61790-4560. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Beam-Hardening Correction for Virtual Monochromatic Imaging of Myocardial Perfusion via Fast-Switchi...
Next Document: Patterns and determinants of dyslipidaemia in 'Young' versus 'Not so Young' patients of coronary art...