Document Detail

Invasive validation of a new oscillometric device (Arteriograph) for measuring augmentation index, central blood pressure and aortic pulse wave velocity.
MedLine Citation:
PMID:  20651604     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The importance of measuring aortic pulse wave velocity (PWVao), aortic augmentation index (Aix) and central systolic blood pressure (SBPao) has been shown under different clinical conditions; however, information on these parameters is hard to obtain. The aim of this study was to evaluate the accuracy of a new, easily applicable oscillometric device (Arteriograph), determining these parameters simultaneously, against invasive measurements.
METHODS: Aortic Aix, SBPao and PWVao were measured invasively during cardiac catheterization in 16, 55 and 22 cases, respectively, and compared with the values measured by the Arteriograph.
RESULTS: We found strong correlation between the invasively measured aortic Aix and the oscillometrically measured brachial Aix on either beat-to-beat or mean value per patient basis (r = 0.9, P < 0.001; r = 0.94, P < 0.001), which allowed the noninvasive calculation of the aortic Aix without using generalized transfer function. Similarly strong correlation (r = 0.95, P < 0.001) was found between the invasively measured and the noninvasively calculated central SBPao; furthermore, the BHS assessment of the paired differences fulfilled the 'B' grading. The PWVao values measured invasively and by Arteriograph were 9.41 ± 1.8 m/s and 9.46 ± 1.8 m/s, respectively (mean ± SD); furthermore, the Pearson's correlation was 0.91 (P < 0.001). The limits of agreement were 11.4% for aortic Aix and 1.59 m/s for PWVao.
CONCLUSION: Aix, SBPao and PWVao, measured oscillometrically, showed strong correlation with the invasively obtained values. The observed limits of agreement are encouragingly low for accepting the method for clinical use. Our results suggest that the PWVao values, measured by Arteriograph, are close to the true aortic PWV, determined invasively.
Iván G Horváth; Adám Németh; Zsófia Lenkey; Nicola Alessandri; Fabrizio Tufano; Pál Kis; Balázs Gaszner; Attila Cziráki
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study; Validation Studies    
Journal Detail:
Title:  Journal of hypertension     Volume:  28     ISSN:  1473-5598     ISO Abbreviation:  J. Hypertens.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-16     Completed Date:  2011-01-18     Revised Date:  2011-03-16    
Medline Journal Info:
Nlm Unique ID:  8306882     Medline TA:  J Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  2068-75     Citation Subset:  IM    
aHeart Institute, Medical School, University of Pécs, Pécs, Hungary bDepartment of Cardiology, University of Rome La Sapienza, Polo Pontino, Italy.
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MeSH Terms
Angiography / instrumentation,  methods*
Aorta / physiology*
Blood Flow Velocity / physiology*
Blood Pressure / physiology*
Brachial Artery / physiology
Elasticity / physiology
Middle Aged
Oscillometry / instrumentation,  methods*
Regional Blood Flow / physiology*
Reproducibility of Results
Comment In:
J Hypertens. 2010 Oct;28(10):2003-6   [PMID:  20844367 ]
J Hypertens. 2011 Mar;29(3):619; author reply 620   [PMID:  21317726 ]

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