Document Detail

Invasive thymoma with osseous metaplasia and cystic change in a case of myasthenia gravis: a rare presentation.
MedLine Citation:
PMID:  21850589     Owner:  NLM     Status:  In-Data-Review    
A 35-year-old woman, a known case of myasthenia gravis, was found to have an anterior mediastinal mass, which was surgically removed. The preoperative clinical and radiologic diagnosis was that of a thymoma, but foci of calcification and prominent cystic change suggested the remote possibility of a teratoma. Histopathologically, it was confirmed to be a type B3 invasive thymoma with intratumoral ossification. Up to the present, three cases of thymoma with osseous metaplasia, including only one with myasthenia gravis, have been reported in the English literature. The present case report highlights the rare occurrence of osseous metaplasia in thymomas and the diagnostic challenge that it can pose, especially if it is associated with cystic degeneration.
Fouzia Siraj; Shashi Dhawan; Deepali Jain
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Publication Detail:
Type:  Journal Article     Date:  2011-08-18
Journal Detail:
Title:  General thoracic and cardiovascular surgery     Volume:  59     ISSN:  1863-6713     ISO Abbreviation:  Gen Thorac Cardiovasc Surg     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101303952     Medline TA:  Gen Thorac Cardiovasc Surg     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  583-6     Citation Subset:  IM    
Department of Pathology, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi, 110060, India.
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