Document Detail

Invasive squamous cell carcinoma arising from chromoblastomycosis.
MedLine Citation:
PMID:  21449695     Owner:  NLM     Status:  MEDLINE    
Chromoblastomycosis is a chronic subcutaneous mycosis seen mainly in tropical regions. While malignant transformation rarely occurs, the present report describes a 69-year-old man with a 21-year history of chromoblastomycosis complicated by invasive squamous cell carcinoma requiring amputation of the affected limb. A review of previous reported cases shows malignancy arising after 20-30 years of infection in ≥60-year-old males who have received inadequate treatment of chromoblastomycosis and have had relapses. An immunocompromised state is not an associated feature of such cases. The extremities are commonly affected as carcinomas occur from the most chronic lesions which are generally found on these limbs.
Adawiyah Jamil; Yin Yin Lee; Suganthi Thevarajah
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2011-03-30
Journal Detail:
Title:  Medical mycology     Volume:  50     ISSN:  1460-2709     ISO Abbreviation:  Med. Mycol.     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2011-12-16     Completed Date:  2012-04-04     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  9815835     Medline TA:  Med Mycol     Country:  England    
Other Details:
Languages:  eng     Pagination:  99-102     Citation Subset:  IM    
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MeSH Terms
Carcinoma, Squamous Cell / diagnosis*,  pathology*,  surgery
Chromoblastomycosis / complications*
Hand / pathology,  radiography,  surgery
Magnetic Resonance Imaging
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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