Document Detail

Invasive procedures for fetal karyotyping: no cause of subsequent gestational hypertension or pre-eclampsia.
MedLine Citation:
PMID:  21126321     Owner:  NLM     Status:  MEDLINE    
The aim was to estimate the risk of maternal hypertensive complications following first- or second-trimester invasive diagnostic procedures, i.e. chorionic villus sampling (CVS) and amniocentesis (AC). Odds ratios (ORs) for gestational hypertension, mild pre-eclampsia or severe pre-eclampsia were calculated for women who underwent CVS (n = 1,984) or AC (n = 21,748) compared with non-exposed women (n = 47,854). No increase in the development of gestational hypertension, mild pre-eclampsia or severe pre-eclampsia was observed. The results do not support an association between invasive procedures for fetal karyotyping and subsequent gestational hypertension or pre-eclampsia.
P Lindgren; M Cederholm; B Haglund; O Axelsson
Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't     Date:  2010-08-17
Journal Detail:
Title:  BJOG : an international journal of obstetrics and gynaecology     Volume:  117     ISSN:  1471-0528     ISO Abbreviation:  BJOG     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-12-03     Completed Date:  2011-01-03     Revised Date:  2011-05-25    
Medline Journal Info:
Nlm Unique ID:  100935741     Medline TA:  BJOG     Country:  England    
Other Details:
Languages:  eng     Pagination:  1422-5     Citation Subset:  AIM; IM    
Copyright Information:
© 2010 The Authors Journal compilation © RCOG 2010 BJOG An International Journal of Obstetrics and Gynaecology.
Centre for Epidemiology, The Swedish National Board of Health and Welfare, Stockholm, Sweden.
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MeSH Terms
Amniocentesis / adverse effects*
Chorionic Villi Sampling / adverse effects*
Hypertension, Pregnancy-Induced / etiology*
Karyotyping / methods*
Maternal Age
Middle Aged
Pre-Eclampsia / etiology*
Risk Assessment
Comment In:
BJOG. 2011 May;118(6):764-5   [PMID:  21481138 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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