Document Detail

Invasive primary ductal apocrine adenocarcinoma of axilla: a case report with immunohistochemical profiling and a review of literature.
MedLine Citation:
PMID:  18713586     Owner:  NLM     Status:  MEDLINE    
Primary cutaneous ductal apocrine adenocarcinoma (PCDAA) is a rare malignant cutaneous neoplasm usually arising in areas of high apocrine gland density. There have been a total of 40 cases of primary apocrine adenocarcinoma reported in the literature; many are indolent and slowly- developing, but some are rapidly progressive. Primary cutaneous ductal apocrine adenocarcinoma has distinctive histologic and immunohistochemical characteristics and the treatment of choice for PCDAA is wide local excision with clear margins. Sentinel lymph node biopsy (SLNB) has also been used to determine prognosis and management. We present a case of a 92-year-old female with a 1-year history of a subcutaneous tumor of the right axilla, histologically consistent with a diagnosis of PCDAA arising in an accessory nipple. To our knowledge this is the first reported case of apocrine adenocarcinoma to develop in an accessory nipple.
Brian Pucevich; Steven Catinchi-Jaime; Jonhan Ho; Drazen M Jukic
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-06-15
Journal Detail:
Title:  Dermatology online journal     Volume:  14     ISSN:  1087-2108     ISO Abbreviation:  Dermatol. Online J.     Publication Date:  2008  
Date Detail:
Created Date:  2008-08-20     Completed Date:  2008-11-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610776     Medline TA:  Dermatol Online J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5     Citation Subset:  IM    
Department of Internal Medicine, Allegheny General Hospital, Pittsburgh, PA, USA.
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MeSH Terms
Adenocarcinoma / metabolism,  pathology*
Aged, 80 and over
Apocrine Glands*
Diagnosis, Differential
Neoplasm Invasiveness
Sweat Gland Neoplasms / metabolism,  pathology*

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