Document Detail

Invasive pneumococcal infections in infants up to three years of age: results of a longitudinal surveillance in North-East Italy.
MedLine Citation:
PMID:  20169833     Owner:  NLM     Status:  MEDLINE    
Pneumococcus is considered one of the main causes of the infections acquired in the community setting and also seems to be the most frequent cause of community-acquired pneumonia in children under 5 years of age. To establish suitable preventive measures as vaccination policy, it would be important to document the incidence of IPD. The main feature of this study was that it demanded a cooperative effort between family pediatricians and those working in the hospitals to estimate the real burden of IPD in children aged 0-36. From 1 January 2003 to 31 December 2003, a prospective active surveillance of clinical cases due to S. pneumoniae was conducted by 87 specifically-trained sentinel pediatricians [all family pediatricians] randomly selected from among those working in North-East Italy. Suspected pneumococcal infections were confirmed by blood cultures at the laboratories of the hospitals involved in the study. 32 cases were suspected, 12 of those proved positive on blood culture and 6 of these 12 confirmed cases were hospitalized. 2 were cases of meningitis, 1 of pneumonia and 9 of bacteremia. The cumulative annual incidence was 58.9 cases/100,000 infants aged 0-36 months (95% CI 30.38-102.71), meaning that North-East Italy can be classified as a mesoendemic area. This study demonstrated that the incidence of IPD in infants aged (0-36 months) is often under-estimated, documenting the importance of prospective active surveillance for assisting rational choices for public health issues.
S Tardivo; A Poli; T Zerman; R D'Elia; G Chiamenti; E Torri; A Bonetti; E Pedevilla; P Pancheri; P Lubrano; R Savastano; G Meneghelli; G Romano
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Annali di igiene : medicina preventiva e di comunit?     Volume:  21     ISSN:  1120-9135     ISO Abbreviation:  Ann Ig     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2010-02-22     Completed Date:  2010-03-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9002865     Medline TA:  Ann Ig     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  619-28     Citation Subset:  IM    
Dipartimento di Medicina e Sanit? Pubblica, Universit? degli Studi di Verona.
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MeSH Terms
Age Factors
Child, Preschool
Community-Acquired Infections / diagnosis,  epidemiology
Infant, Newborn
Italy / epidemiology
Longitudinal Studies
Meningitis, Pneumococcal / diagnosis,  epidemiology
Pneumococcal Infections / diagnosis,  epidemiology*
Pneumonia, Pneumococcal / diagnosis,  epidemiology
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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