Document Detail

Invasive functional testing.
MedLine Citation:
PMID:  20542834     Owner:  NLM     Status:  MEDLINE    
The concept of "significant" coronary stenosis has been revisited since the introduction of physiological measurements in the cardiac catheterisation laboratory. Invasive functional testing evaluates coronary physiology by recording blood pressure, flow or velocity and yields important information about the epicardial arteries and the respective myocardial territory. Numerous clinical studies have demonstrated the value of physiological testing in the assessment of challenging angiographic subsets, such as multivessel disease, bifurcation lesions and diffuse coronary atherosclerosis. In selected cases, deferral of revascularisation on the basis of functional indices can actually decrease adverse cardiac events. Furthermore, physiological measurements after angioplasty and stent implantation can be used to optimise the angiographic results and improve patient outcome. This review will discuss the basic concepts of functional testing in the catheterisation laboratory and its main applications for the interventional cardiologist.
Stella-Lida Papadopoulou; Chrysafios Girasis
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology     Volume:  6 Suppl G     ISSN:  1969-6213     ISO Abbreviation:  EuroIntervention     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-06-14     Completed Date:  2010-09-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101251040     Medline TA:  EuroIntervention     Country:  France    
Other Details:
Languages:  eng     Pagination:  G79-86     Citation Subset:  IM    
Department of Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands.
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MeSH Terms
Blood Flow Velocity
Coronary Angiography
Coronary Circulation*
Coronary Stenosis / diagnosis*,  physiopathology,  therapy
Diagnostic Imaging* / methods
Fractional Flow Reserve, Myocardial
Heart Catheterization*
Hyperemia / physiopathology
Laser-Doppler Flowmetry
Middle Aged
Predictive Value of Tests
Severity of Illness Index
Treatment Outcome
Vasodilator Agents / diagnostic use
Reg. No./Substance:
0/Vasodilator Agents

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