| Invasive cervical cancer in pregnancy. | |
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MedLine Citation:
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PMID: 8717566 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cervical cancer is the commonest malignancy which complicates pregnancy, but the management remains controversial. We reviewed our patients in an attempt to identify the best management options which resulted in long-term survival for the mother and a live baby. The total number of pregnancies managed between January, 1981 and March, 1995 was obtained from the hospital records, and patients with invasive cervical cancer diagnosed during pregnancy or within 12 months of delivery were identified. The case records were reviewed. Between January, 1981 and March, 1995 there were 22 cases of cervical cancer diagnosed either during pregnancy or within 12 months postpartum. This gave an incidence of cervical cancer associated with pregnancy of 1 in 3,817 pregnancies or 0.26 per 1,000 pregnancies. Eleven patients had microinvasive disease. Nine were treated by cone biopsy and 2 by radical hysterectomy. Nine patients had Stage 1B and 1 had Stage 2A disease and all were treated with radical hysterectomy. One patient had Stage 3B disease and was treated with radiotherapy and chemotherapy followed by simple hysterectomy. Fourteen patients delivered vaginally. Twenty of the 22 patients were delivered of live babies which survived. The patients have been followed from 1 month to 13 years with only 1 recurrence, and all 22 remain alive. We conclude that all pregnant women should have a Pap smear performed antenatally. Cone biopsy can be safely performed in pregnancy and may be adequate treatment for microinvasive squamous cell carcinomas. Treatment, including the timing of delivery, must be individualized, with the patient playing an important decision-making role. |
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Authors:
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D G Allen; R S Planner; P T Tang; J P Scurry; T Weerasiri |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Australian & New Zealand journal of obstetrics & gynaecology Volume: 35 ISSN: 0004-8666 ISO Abbreviation: Aust N Z J Obstet Gynaecol Publication Date: 1995 Nov |
Date Detail:
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Created Date: 1996-11-29 Completed Date: 1996-11-29 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0001027 Medline TA: Aust N Z J Obstet Gynaecol Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 408-12 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, University of Melbourne, Victoria. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
/
pathology,
therapy* Adult Carcinoma, Squamous Cell / pathology, therapy* Female Humans Hysterectomy Neoplasm Invasiveness Pregnancy Pregnancy Complications, Neoplastic / pathology, therapy* Retrospective Studies Treatment Outcome Uterine Cervical Neoplasms / pathology, therapy* |
| Comments/Corrections | |
Comment In:
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Aust N Z J Obstet Gynaecol. 1996 Nov;36(4):496-7
[PMID:
9006848
]
Aust N Z J Obstet Gynaecol. 1996 May;36(2):228 [PMID: 8798329 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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