Document Detail


Invasion of campylobacter-like organisms in the duodenal mucosa in patients with active duodenal ulcer.
MedLine Citation:
PMID:  3573680     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The ultrastructure of campylobacter-like organisms found within duodenal biopsy specimens from 7 of 24 patients (28%) with active duodenal ulcer is described. Their curved shape and variable size are similar to what has previously been reported in descriptions of light microscopies. The organisms were found at the edge of active duodenal ulcers exclusively near neutral-mucous producing antral cells, to which they can adhere. The presence of these bacteria within cells and in the intercellular fluid implies that they can penetrate through the cell membrane or through tight intercellular junctions. The occurrence of these bacteria as well as numerous polymorphonuclear leukocytes in the afflicted regions suggests that the bacteria originally described by Warren and Marshall are indeed pathogenic and that their influence on ulcer healing should be included in designing treatment protocols.
Authors:
G Bode; P Malfertheiner; H Ditschuneit
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Klinische Wochenschrift     Volume:  65     ISSN:  0023-2173     ISO Abbreviation:  Klin. Wochenschr.     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-05-28     Completed Date:  1987-05-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985205R     Medline TA:  Klin Wochenschr     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  144-6     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Campylobacter / ultrastructure
Campylobacter Infections / microbiology*
Duodenal Ulcer / microbiology*
Duodenum / microbiology
Humans
Intestinal Mucosa / microbiology*
Microscopy, Electron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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