Document Detail


Introduction of histidine units using benzotriazolide activation.
MedLine Citation:
PMID:  23322621     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
N(α) -Boc-N(im) -(4-toluenesulfonyl-l-histidylbenzotriazole) enables convenient acylation of N-, O-, S-, and C-nucleophiles with no detectable racemization. We report efficient syntheses of novel histidine-containing di-, tri-, and tetra-peptides and models for the preparation of potentially biologically active histidine N-, O-, S-, and C-conjugates. Copyright © 2013 European Peptide Society and John Wiley & Sons, Ltd.
Authors:
Kiran Bajaj; Siva S Panda; Mohamed A Ibrahim; Said A El-Feky; Alan R Katritzky
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-16
Journal Detail:
Title:  Journal of peptide science : an official publication of the European Peptide Society     Volume:  -     ISSN:  1099-1387     ISO Abbreviation:  J. Pept. Sci.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9506309     Medline TA:  J Pept Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 European Peptide Society and John Wiley & Sons, Ltd.
Affiliation:
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL, 32611-7200, USA.
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