Document Detail


Introducing chemists to food allergy.
MedLine Citation:
PMID:  11297997     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Adverse reactions to food may be toxic or non toxic, depending on the susceptibility to a certain food; non toxic reactions that involve immune mechanisms are termed allergy if they are IgE-mediated. If no immunological mechanism is responsible, it is termed intolerance. The following disorders are considered a consequence of food allergy: gastrointestinal reactions (oral allergy syndrome, vomiting, diarrhea, protein-induced enterocolitic syndrome, eosinophilic gastroenteritis); respiratory reactions (rhinitis, asthma, laryngeal edema); cutaneous reactions (urticaria-angioedema, atopic dermatitis); anaphylaxis. There is much recent evidence to consider celiac disease an immunological disorder. Food allergy diagnosis is based on history, SPT, specific IgE, food challenges. DBPCFC is fundamental for diagnosing true food allergy; patients who have had anaphylaxis to food must not undergo DBPCFC. Rapidly progressive respiratory reactions and anaphylactic shock are life-threatening reactions that can be caused by food allergy. The doses of food inducing anaphylaxis can be very low, therefore commercial cross-contamination with an unsuspected food during food processing can be risky for the food allergic patient. The prevention of severe anaphylactic food reactions may lie in interdisciplinary collaboration among allergologists, chemists, food technologists, and experts in food industry research.
Authors:
C Ortolani; M Ispano; J Scibilia; E A Pastorello
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Allergy     Volume:  56 Suppl 67     ISSN:  0105-4538     ISO Abbreviation:  Allergy     Publication Date:  2001  
Date Detail:
Created Date:  2001-04-12     Completed Date:  2001-08-16     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7804028     Medline TA:  Allergy     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  5-8     Citation Subset:  IM    
Affiliation:
Centro di Allergologia e Immunologia Clinica, Ospedale Niguarda Cà Granda, Milan, Italy. allergologia@ospedale-niguarda.it
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MeSH Terms
Descriptor/Qualifier:
Allergens / adverse effects
Food Hypersensitivity / diagnosis,  epidemiology,  etiology*,  immunology*
Humans
Prevalence
Chemical
Reg. No./Substance:
0/Allergens

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