Document Detail


Intrinsic labelling of chicken meat with stable isotopes of zinc, for intended use in human feeding studies: feasibility and design considerations.
MedLine Citation:
PMID:  7317337     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. The feasibility of intrinsically labelling poultry meat with the stable isotopes 68Zn and 70Zn was investigated. 2. Chickens (1-d-old) were gavaged with solutions of 68Zn and 70Zn several times over a 42 d period. 3. Isotopic analysis of edible tissues has shown that they were significantly enriched with respect to the gavaged isotope and that the extent of isotopic enrichment achieved was sufficient to permit their use in human feeding experiments designed to investigate availability of native Zn from such food models. 4. The absolute efficiency of retention of the stable isotopes from gavage solutions in the edible tissues has been calculated to be 2-3% of the administered dose; methods have been suggested to enhance this value, based on considerations of utilization of dietary Zn.
Authors:
M Janghorbani; B T Ting; V R Young; F H Steinke
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The British journal of nutrition     Volume:  46     ISSN:  0007-1145     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  1981 Nov 
Date Detail:
Created Date:  1982-03-13     Completed Date:  1982-03-13     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  395-402     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Chickens
Humans
Intestinal Absorption
Isotope Labeling*
Meat
Nutritive Value
Tissue Distribution
Zinc / metabolism
Zinc Isotopes*
Grant Support
ID/Acronym/Agency:
1-RO1-CA-27917-01/CA/NCI NIH HHS
Chemical
Reg. No./Substance:
0/Zinc Isotopes; 7440-66-6/Zinc

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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