Document Detail


Intrinsic fluorescence polarization of amniotic fluid: evaluation of human fetal lung maturity.
MedLine Citation:
PMID:  12945576     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article reports a novel approach for the evaluation of fetal lung maturity based on fluorescence polarization (FP). The technique determines the intrinsic fluorescence polarization ratio (IFPR) of the amniotic fluid (AF). In vitro measurements of the IFPR indicate a clear dichotomy: high values for young pregnancies and low values for mature pregnancies. The new method has the potential to be a noninvasive procedure because the excitation of the AF and the collection of its fluorescence emission can be performed through the intact cervical amniotic membranes.
Authors:
Jonathan Molcho; Hemy Avraham; Rivka Cohen-Luria; Abraham H Parola
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Photochemistry and photobiology     Volume:  78     ISSN:  0031-8655     ISO Abbreviation:  Photochem. Photobiol.     Publication Date:  2003 Aug 
Date Detail:
Created Date:  2003-08-29     Completed Date:  2003-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376425     Medline TA:  Photochem Photobiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  105-8     Citation Subset:  IM    
Affiliation:
Faculty of Engineering Sciences, The Department of Electrical and Computer Engineering, Ben Gurion University of the Negev, Beer Sheva, Israel. molcho@ee.bgu.ac.il
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MeSH Terms
Descriptor/Qualifier:
Amniotic Fluid / chemistry*
Female
Fetal Organ Maturity / physiology*
Fluorescence Polarization / methods*
Gestational Age
Humans
Lung / embryology*
Pregnancy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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