Document Detail

Intrinsic positive end-expiratory pressure at various frequencies of supraglottic jet ventilation in a model of dynamic upper airway obstruction.
MedLine Citation:
PMID:  20601451     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Supraglottic jet ventilation (JV(S)) with injectors above airway stenoses may result in inadvertent high lung pressures. We designed this study to investigate intrinsic positive end-expiratory pressure (PEEP(i)) during jet ventilation via a distant injector in a model of dynamic upper airway obstruction.
METHODS: Respiratory pressure-time curves were recorded during JV(S) in a tracheal lung model using a pig's trachea and an embolectomy catheter's air-filled balloon to simulate 60 and 80% airway obstruction. JV(S) was performed at various jet frequencies (F(jet) 30 min(-1), 60 min(-1), and 100 min(-1)) and driving pressures (1 bar and 2 bar).
RESULTS: JV(S) was associated with generation of PEEP(i), which depended on driving pressure, the degree of obstruction, and on ventilatory frequency.
CONCLUSIONS: In the presence of a dynamic upper airway obstruction, JV(S) via a distant injector may result in PEEP(i), which cannot be detected when airway pressure is measured in front of the obstruction.
Gerald C Ihra; Ching-Ju Tsai; Oliver Kimberger
Publication Detail:
Type:  Journal Article     Date:  2010-07-02
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  111     ISSN:  1526-7598     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-24     Completed Date:  2010-09-10     Revised Date:  2011-02-26    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  703-6     Citation Subset:  AIM; IM    
Department of Anesthesia, Intensive Care Medicine and Pain Therapy, Medical University Vienna, Waehringer Guertel 18-20, AKH 9i, A-1090 Vienna, Austria.
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MeSH Terms
Airway Obstruction / therapy*
High-Frequency Jet Ventilation*
Models, Anatomic
Positive-Pressure Respiration*
Tracheal Diseases / therapy

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