Document Detail

Minireview: Intrinsic and extrinsic factors in thyroid gland development: an update.
MedLine Citation:
PMID:  21693675     Owner:  NLM     Status:  MEDLINE    
In vertebrates the portion of the thyroid gland synthesizing the thyroid hormones develops from a small group of endodermal cells in the foregut. The nature of the signals that lead to the biochemical and morphogenetic events responsible for the organization of these cells into the adult thyroid gland has only recently become evident. In this review we summarize recent developments in the understanding of these processes, derived from evidence collected in several organisms.
Mario De Felice; Roberto Di Lauro
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2011-06-21
Journal Detail:
Title:  Endocrinology     Volume:  152     ISSN:  1945-7170     ISO Abbreviation:  Endocrinology     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-25     Completed Date:  2011-09-21     Revised Date:  2011-11-24    
Medline Journal Info:
Nlm Unique ID:  0375040     Medline TA:  Endocrinology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2948-56     Citation Subset:  AIM; IM    
Biogem, 83031 Ariano Irpino (AV), Italy.
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MeSH Terms
Cell Survival
Fibroblast Growth Factors / physiology
Nuclear Proteins / physiology
Paired Box Transcription Factors / physiology
Signal Transduction
Stem Cells / cytology
Thyroid Gland / cytology,  embryology*
Transcription Factors / physiology
Tretinoin / physiology
Grant Support
Reg. No./Substance:
0/Nuclear Proteins; 0/PAX8 protein, human; 0/Paired Box Transcription Factors; 0/Transcription Factors; 0/thyroid nuclear factor 1; 302-79-4/Tretinoin; 62031-54-3/Fibroblast Growth Factors

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