Document Detail


Intravitreal triamcinolone acetonide in patients with macular oedema due to branch retinal vein occlusion: a pilot study.
MedLine Citation:
PMID:  16188000     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To evaluate treatment of macular oedema due to branch retinal vein occlusion (BRVO) with intravitreal triamcinolone acetonide. METHODS: In a prospective case series, nine patients with macular oedema due to BRVO received an intravitreal injection of 4 mg triamcinolone acetonide. Examination included best-corrected visual acuity (BCVA) for distance and reading, intraocular pressure (IOP) measurement, fluorescein angiography and high resolution imaging by optical coherence tomography, preoperatively and at 1 week, 1 month, 3 and 6 months postoperatively. RESULTS: Preoperative mean BCVAs were 1.3 +/- 0.8 for distance vision, and 1.1 +/- 0.3 for reading acuity, respectively. A significant improvement in reading acuity was observed until 1 month (0.7 +/- 0.4, p = 0.02). No significant reduction in mean macular thickness was observed. CONCLUSIONS: Intravitreal injection of triamcinolone acetonide led to a significant improvement in mean VA in patients with macular oedema due to BRVO. However, the significant effect was not permanent and persisted for only 1 month.
Authors:
Katharina Krepler; Erdem Ergun; Stefan Sacu; Sibylla Richter-Müksch; Julia Wagner; Michael Stur; Andreas Wedrich
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta ophthalmologica Scandinavica     Volume:  83     ISSN:  1395-3907     ISO Abbreviation:  Acta Ophthalmol Scand     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-09-28     Completed Date:  2005-12-01     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  9507578     Medline TA:  Acta Ophthalmol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  600-4     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. katharina.krepler@meduniwien.ac.at
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MeSH Terms
Descriptor/Qualifier:
Aged
Fluorescein Angiography
Glucocorticoids / administration & dosage,  therapeutic use*
Humans
Injections
Intraocular Pressure / physiology
Macular Edema / drug therapy*,  etiology,  physiopathology
Pilot Projects
Prospective Studies
Retinal Vein Occlusion / complications,  drug therapy*,  physiopathology
Tomography, Optical Coherence
Triamcinolone Acetonide / administration & dosage,  therapeutic use*
Visual Acuity / physiology
Vitreous Body
Chemical
Reg. No./Substance:
0/Glucocorticoids; 76-25-5/Triamcinolone Acetonide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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