Document Detail


Intravitreal bevacizumab for iatrogenic choroidal neovascularization due to laser photocoagulation in central serous chorioretinopathy.
MedLine Citation:
PMID:  22526618     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Choroidal neovascularization (CNV) is well recognized as a complication of laser photocoagulation for central serous chorioretinopathy (CSC). However, little is known about its management.
PATIENTS: Two patients who developed iatrogenic CNV after laser photocoagulation for CSC.
OBSERVATIONS: A single intravitreal bevacizumab (IVB) injection was given in both cases. The best-corrected visual acuity (BCVA) of 1 of the patients improved from 0.3 to 0.5 on the following day and to 1.2 three months after the IVB, and the BCVA of the other patient improved from 0.5 to 1.0 two weeks after the IVB. In both cases, the CNV became inactive 1 month after IVB on fluorescein angiography and remained stable for over 1 year.
CONCLUSION: IVB was beneficial for iatrogenic CNV that developed after laser photocoagulation for CSC.
Authors:
Yoko Nomura; Ryo Obata; Yasuo Yanagi
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2012-04-20
Journal Detail:
Title:  Japanese journal of ophthalmology     Volume:  56     ISSN:  1613-2246     ISO Abbreviation:  Jpn. J. Ophthalmol.     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-05-15     Completed Date:  2012-07-26     Revised Date:  2013-05-27    
Medline Journal Info:
Nlm Unique ID:  0044652     Medline TA:  Jpn J Ophthalmol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  245-9     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, University of Tokyo School of Medicine, 7-3-1 Hongo, Tokyo, 113-8655, Japan. nomurayoko-tky@umin.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Angiogenesis Inhibitors / administration & dosage*
Antibodies, Monoclonal, Humanized / administration & dosage*
Central Serous Chorioretinopathy / surgery*
Choroidal Neovascularization / drug therapy*,  etiology,  physiopathology
Fluorescein Angiography
Humans
Iatrogenic Disease*
Intravitreal Injections
Laser Coagulation / adverse effects*
Male
Middle Aged
Tomography, Optical Coherence
Vascular Endothelial Growth Factor A / antagonists & inhibitors
Visual Acuity / physiology
Chemical
Reg. No./Substance:
0/Angiogenesis Inhibitors; 0/Antibodies, Monoclonal, Humanized; 0/VEGFA protein, human; 0/Vascular Endothelial Growth Factor A; 2S9ZZM9Q9V/bevacizumab

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