Document Detail

Intraventricular hemorrhage in the newborn beagle puppy. A limited model of intraventricular hemorrhage in the premature infant.
MedLine Citation:
PMID:  3125529     Owner:  NLM     Status:  MEDLINE    
The term beagle puppy has been used extensively as an experimental model of intraventricular hemorrhage (IVH) in the preterm infant. Fourteen variables were selected which were considered theoretically important to both the model and the preterm infant, and the data were subjected to discriminant analysis. Use of only three variables in combination correctly predicted whether an animal would sustain germinal matrix hemorrhage: baseline blood pressure, Pco2, and temperature. The model does not involve ischemia, which appears to be the sentinel but not singular insult in the IVH of preterm infants.
D L Johnson; P Getson; C Shaer; R O'Donnell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric neuroscience     Volume:  13     ISSN:  0255-7975     ISO Abbreviation:  Pediatr Neurosci     Publication Date:  1987  
Date Detail:
Created Date:  1988-04-01     Completed Date:  1988-04-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8601677     Medline TA:  Pediatr Neurosci     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  78-83     Citation Subset:  IM    
Department of Neurosurgery, Children's Hospital National Medical Center, Washington, D.C.
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MeSH Terms
Animals, Newborn / physiology*
Blood Pressure
Body Temperature
Carbon Dioxide / blood
Cerebral Hemorrhage / physiopathology,  prevention & control,  veterinary*
Cerebral Ventricles
Disease Models, Animal*
Dog Diseases / prevention & control*
Infant, Newborn
Infant, Premature*
Partial Pressure
Reg. No./Substance:
124-38-9/Carbon Dioxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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