Document Detail

Intraventricular fungus ball: a unique manifestation of refractory intracranial candidiasis in an immunocompetent neonate.
MedLine Citation:
PMID:  19951049     Owner:  NLM     Status:  MEDLINE    
The authors report on a case of intracranial candidiasis in an immunocompetent neonate with a ventriculo-peritoneal shunt. The child was known to be colonized with yeast as she had been treated for oral thrush; however, she did not have systemic candidiasis. Despite initial treatment with antifungal medication, intraventricular fungus balls developed that were visible on imaging and confirmed with pathological analysis. Multiple endoscopic intraventricular operations were required for excision of the initial and recurrent fungus balls, multiple fenestrations of loculations and cysts were performed, and ultimately 3 ventriculoperitoneal shunts were placed. The finding of an intraventricular fungus ball is a unique manifestation of intracranial candidiasis, and to the authors' knowledge has not been previously reported in the English literature.
Mandy J Binning; Janet Lee; Emily A Thorell; Jay K Riva-Cambrin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neurosurgery. Pediatrics     Volume:  4     ISSN:  1933-0715     ISO Abbreviation:  -     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-02     Completed Date:  2009-12-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101463759     Medline TA:  J Neurosurg Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  584-7     Citation Subset:  IM    
Department of Neurosurgery, Primary Children's Medical Center, University of Utah, Salt Lake City, Utah, USA.
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MeSH Terms
Administration, Oral
Amphotericin B / administration & dosage
Antifungal Agents / administration & dosage
Brain Diseases / diagnosis*,  drug therapy,  pathology,  surgery
Candidiasis / diagnosis*,  drug therapy,  pathology,  surgery
Echinocandins / administration & dosage
Fluconazole / administration & dosage
Infant, Newborn
Injections, Spinal
Magnetic Resonance Imaging
Postoperative Care
Ventriculoperitoneal Shunt
Reg. No./Substance:
0/Antifungal Agents; 0/Echinocandins; 0/caspofungin; 1397-89-3/Amphotericin B; 86386-73-4/Fluconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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