| Intraventricular Hemorrhage and Developmental Outcomes at 24 Months of Age in Extremely Preterm Infants. | |
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MedLine Citation:
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PMID: 22232137 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Whether intraventricular hemorrhage increases the risk of adverse developmental outcome among premature infants is controversial. Using brain ultrasound, we identified intraventricular hemorrhage and white matter abnormalities among 1064 infants born before 28 weeks' gestation. We identified adverse developmental outcomes at 24 months of age using a standardized neurologic examination and the Bayley Scales of Infant Development Mental and Motor Scales. In logistic regression models that adjusted for gestational age, sex, and public insurance, isolated intraventricular hemorrhage was associated with visual fixation difficulty but no other adverse outcome. Infants who had a white matter lesion unaccompanied by intraventricular hemorrhage were at increased risk of cerebral palsy, low Mental and Motor Scores, and visual and hearing impairments. Except when accompanied or followed by a white matter lesion, intraventricular hemorrhage is associated with no more than a modest increase (and possibly no increase) in the risk of adverse developmental outcome during infancy. |
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Authors:
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T Michael O'Shea; Elizabeth N Allred; Karl C K Kuban; Deborah Hirtz; Barbara Specter; Sara Durfee; Nigel Paneth; Alan Leviton; |
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Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Journal of child neurology Volume: 27 ISSN: 1708-8283 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8606714 Medline TA: J Child Neurol Country: - |
Other Details:
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Languages: ENG Pagination: 22-29 Citation Subset: - |
Affiliation:
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1Wake Forest School of Medicine, Winston-Salem, NC, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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