| Intravenous thrombolysis followed by intra-arterial thrombolysis and mechanical thrombectomy for the treatment of pediatric ischemic stroke. | |
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MedLine Citation:
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PMID: 18722630 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Experience with systemic or selective local administration of thrombolytic agents in pediatric ischemic stroke is limited to sporadic case reports, since patients of age less than 18 years were systematically excluded from randomised controlled trials. We report a case of childhood IS attributable to the terminal internal carotid artery occlusion that was treated successfully with mechanical thrombectomy which followed unsuccessful attempts to recanalize the artery with intravenous and intra-arterial thrombolytics. Combined systemic and intra-arterial thrombolysis followed by mechanical thrombectomy can be feasible and may be considered as means of achieving reperfusion in pediatric ischemic stroke patients with persisting arterial occlusion. |
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Authors:
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Georgios Tsivgoulis; Joseph A Horton; Jayne M Ness; Damon Patterson; Mary Brethour; Juan Carlos Abanses; Andrei V Alexandrov |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-08-23 |
Journal Detail:
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Title: Journal of the neurological sciences Volume: 275 ISSN: 0022-510X ISO Abbreviation: J. Neurol. Sci. Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-11-17 Completed Date: 2009-04-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: Netherlands |
Other Details:
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Languages: eng Pagination: 151-3 Citation Subset: IM |
Affiliation:
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Comprehensive Stroke Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama, USA. tsivgoulisgiorg@yahoo.gr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angiography
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methods Cerebral Angiography / methods Child Diffusion Magnetic Resonance Imaging Drug Administration Routes Fibrinolytic Agents / administration & dosage* Humans Male Stroke / drug therapy*, pathology, surgery* Thrombectomy / methods* Thrombolytic Therapy Ultrasonography, Doppler, Transcranial / methods |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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