Document Detail


Intravenous streptokinase in acute myocardial infarction.
MedLine Citation:
PMID:  6861625     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Intracoronary streptokinase has been reported to be successful in producing coronary recanalization and lowered morbidity and mortality in acute myocardial infarction patients, when administered shortly after the onset of chest pain. However, intracoronary administration of streptokinase is not practical for most hospitals at present, and intravenous administration would enable treatment of larger numbers of patients and enable the drug to be administered earlier than by the intracoronary route. Available studies have suggested benefits of the intravenous route and results of randomized clinical trials indicate an approximately 20-percent decrease in mortality after intravenous use. Intravenous streptokinase after acute myocardial infarction warrants further investigation.
Authors:
C S Conner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Drug intelligence & clinical pharmacy     Volume:  17     ISSN:  0012-6578     ISO Abbreviation:  Drug Intell Clin Pharm     Publication Date:  1983 May 
Date Detail:
Created Date:  1983-08-11     Completed Date:  1983-08-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0212457     Medline TA:  Drug Intell Clin Pharm     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  367-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Humans
Infusions, Parenteral
Myocardial Infarction / drug therapy*
Streptokinase / administration & dosage*
Chemical
Reg. No./Substance:
EC 3.4.-/Streptokinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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