Document Detail

Intravenous streptokinase in acute myocardial infarction.
MedLine Citation:
PMID:  3375938     Owner:  NLM     Status:  MEDLINE    
The safety and efficacy of streptokinase (STK) (Kabikinase; Keatings) in restoring vessel patency in 70 patients with acute myocardial infarction are reported. Return of vessel patency occurred more frequently (76%) in patients receiving STK than in patients in a control group (12%) (P = 0.001). The main complication was bleeding, which invariably resulted from invasive procedures. Dangerous dysrhythmias were uncommon and no fatalities were caused by STK administration. It is recommended that thrombolytic therapy be started as early as possible in patients with acute myocardial infarction, who can then be referred to centres equipped for coronary angiography for further management. Unnecessary invasive procedures should be avoided.
J M Bennett; F J van Niekerk; J Gourassas; S Konstantinides; J C Badenhorst
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  73     ISSN:  0256-9574     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-06-24     Completed Date:  1988-06-24     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  513-5     Citation Subset:  IM    
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MeSH Terms
Arrhythmias, Cardiac / chemically induced
Infusions, Intravenous
Middle Aged
Myocardial Infarction / drug therapy*
Streptokinase / administration & dosage*,  adverse effects
Reg. No./Substance:
EC 3.4.-/Streptokinase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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