Document Detail


Intravenous immunoglobulin therapy of lupus pneumonitis.
MedLine Citation:
PMID:  18057686     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute lupus pneumonitis in an 11-year-old girl with lupus nephritis is reported. Chest radiograph and arterial blood gas parameters were suggestive of Acute Respiratory Distress Syndrome (ARDS). Definitive pulmonary infection was excluded by investigations and poor clinical response to antibiotics. The respiratory worsening warranted ventilatory support with very high pressures. A trial of intravenous immunoglobulin was given following which there was improvement in the ventilatory requirements by 36 hours. The child was successfully weaned off ventilator and discharged from ICU by day 7. The role of intravenous immunoglobulin during acute life threatening pulmonary emergencies in a case of SLE prompted this clinical brief.
Authors:
G Chetan; S Mahadevan; Kikon Sulanthung; P Narayanan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  74     ISSN:  0973-7693     ISO Abbreviation:  Indian J Pediatr     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-12-06     Completed Date:  2007-12-17     Revised Date:  2009-07-15    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  1032-3     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry, India.
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MeSH Terms
Descriptor/Qualifier:
Child
Combined Modality Therapy
Female
Humans
Immunoglobulins, Intravenous / therapeutic use*
Lupus Nephritis / complications
Pneumonia / complications,  therapy*
Positive-Pressure Respiration*
Chemical
Reg. No./Substance:
0/Immunoglobulins, Intravenous

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