Document Detail

Intravenous immunoglobulin for recurrent unexplained pregnancy loss: a case report.
MedLine Citation:
PMID:  17879838     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Recurrent unexplained pregnancy loss plagues obstetricians. Many therapies are controversial, including intravenous immunoglobulin (IVIG). There have been limited studies to support or oppose its use. CASE: A 33-year-old woman, gravida 12, para 0, 2, 10, 1, with normal laboratory values and normal parental karyotypes, unsuccessfully tried many different accepted therapies for recurrent pregnancy loss. She tried IVIG with the last pregnancy and achieved delivery of a viable, male infant at 32 weeks' gestation. CONCLUSION: For many cases of unexplained recurrent pregnancy loss, IVIG may not be the answer. However, this case may demonstrate a limited role for IVIG in the treatment of recurrent pregnancy loss with repeated maternal floor infarction of the placenta. Deciding whether or not to use IVIG should not be the question; the real question may be when to use it.
Kris Barnsfather; Marcello Pietrantoni
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  52     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-09-20     Completed Date:  2007-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  737-40     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, USA.
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MeSH Terms
Abortion, Habitual / etiology,  therapy*
Immunoglobulins, Intravenous / therapeutic use*
Infant, Newborn
Infarction / complications
Placenta / blood supply
Pregnancy Outcome
Reg. No./Substance:
0/Immunoglobulins, Intravenous

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