| Intravenous immunoglobulin (GB-0998) for prophylaxis of recurrent acute otitis media and lower respiratory tract infection in infancy with IgG 2 deficiency | |
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MedLine Citation:
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PMID: 9666680 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The prophylactic effect of intravenous immunoglobulin (GB-0998) on the recurrent acute otitis media, bronchitis and bronchopneumonia in IgG 2 deficient infants was investigated in a multicenter trial. GB-0998 was administered 6 times every 4 weeks. The doses were 300 mg/kg wt. during the first treatment, followed by 5 doses of 200 mg/kg wt. The results indicated that GB-0998 was effective in the prophylaxis of the recurrent infection of acute otitis media, bronchitis and bronchopneumonia in infancy with IgG 2 deficiency and/or IgG 2 antibody deficiency specific for Streptococcus pneumoniae. |
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Authors:
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Y Sakiyama; A Komiyama; K Shiraki; N Taniguchi; S Torii; S Baba; J Yata; S Matsumoto |
Publication Detail:
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Type: Clinical Trial; English Abstract; Journal Article; Multicenter Study |
Journal Detail:
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Title: Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology Volume: 21 ISSN: 0911-4300 ISO Abbreviation: Nihon Rinsho Meneki Gakkai Kaishi Publication Date: 1998 Apr |
Date Detail:
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Created Date: 1998-09-18 Completed Date: 1998-09-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9505992 Medline TA: Nihon Rinsho Meneki Gakkai Kaishi Country: JAPAN |
Other Details:
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Languages: jpn Pagination: 70-9 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, School of Medicine, Hokkaido University. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Bronchitis / prevention & control* Child, Preschool Female Humans IgG Deficiency / therapy* Immunoglobulins, Intravenous / therapeutic use* Infant Male Otitis Media / prevention & control* Pneumonia / prevention & control* Recurrence |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulins, Intravenous |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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