| Intravenous flunitrazepam for status epilepticus. | |
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MedLine Citation:
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PMID: 2515734 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Flunitrazepam (FZP) was administered intravenously, with success, to two patients with status epilepticus. Case 1 was a patient with a tonic-clonic status epilepticus. Intravenous phenytoin had no effect. Case 2 had minor status epilepticus. With the intravenous administration of FZP, diluted 1:10 with distilled water at a dose of 0.03 mg/kg at a slow rate, both patients were relieved of the status epilepticus. Unlike diazepam, FZP neither looks cloudy when diluted with distilled water nor causes angialgia. No disturbances in circulation or respiration occurred. Considering that FZP has a strong anticonvulsant action on status epilepticus, it can be expected to be a useful therapeutic agent for status epilepticus in infants and children. |
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Authors:
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K Sumi; T Nagaura; N Sakata; T Nishigaki; M Akagi |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta paediatrica Japonica; Overseas edition Volume: 31 ISSN: 0374-5600 ISO Abbreviation: Acta Paediatr Jpn Publication Date: 1989 Oct |
Date Detail:
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Created Date: 1990-03-09 Completed Date: 1990-03-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370357 Medline TA: Acta Paediatr Jpn Country: JAPAN |
Other Details:
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Languages: eng Pagination: 563-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Child Child, Preschool Electroencephalography Female Flunitrazepam / administration & dosage* Humans Injections, Intravenous Status Epilepticus / drug therapy* |
| Chemical | |
Reg. No./Substance:
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1622-62-4/Flunitrazepam |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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