| Intravenous dipyridamole: use in thallous chloride TL 201 stress imaging. | |
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MedLine Citation:
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PMID: 1803798 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An intravenous form of dipyridamole has been approved for cardiac stress testing with thallous chloride Tl 201 (201Tl) imaging. The procedure provides an alternative method for stress testing of patients who cannot perform strenuous physical exercise because of physical limitations or those in the immediate postinfarction period. Dipyridamole simulates the physiologic effects of physical exercise by increasing adenosine concentrations, which in turn increases coronary blood flow. Dipyridamole maximizes the differences in uptake of radioactive thallium in myocardial regions supplied by normal coronary arteries and those distal to stenosed arteries where blood flow is reduced. The sensitivity and specificity of dipyridamole-201Tl stress imaging for the detection of coronary disease are comparable to those of traditional exercise-201Tl stress testing. The intravenous dipyridamole usually is well tolerated, and the majority of adverse effects can be reversed with the administration of aminophylline. |
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Authors:
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P A Howard |
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Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: DICP : the annals of pharmacotherapy Volume: 25 ISSN: 1042-9611 ISO Abbreviation: DICP Publication Date: 1991 Oct |
Date Detail:
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Created Date: 1992-04-28 Completed Date: 1992-04-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8904338 Medline TA: DICP Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1085-91 Citation Subset: IM |
Affiliation:
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Department of Pharmacy Practice, University of Kansas Medical Center, Kansas City 66103. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Coronary Disease
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radionuclide imaging Dipyridamole / diagnostic use* Exercise Test Heart / radionuclide imaging* Heart Function Tests Humans Infusions, Intravenous Sensitivity and Specificity Thallium / diagnostic use Thallium Radioisotopes / diagnostic use* |
| Chemical | |
Reg. No./Substance:
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0/Thallium Radioisotopes; 58-32-2/Dipyridamole; 7440-28-0/Thallium; 7791-12-0/thallium chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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