| Intravenous dextrose during outpatient rehydration in pediatric gastroenteritis. | |
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MedLine Citation:
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PMID: 17296801 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Rapid intravenous (IV) rehydration in the emergency department (ED) is required for certain children with acute gastroenteritis (AGE). OBJECTIVES: To determine whether the amount of IV dextrose administered is related to a return visit with admission (RVA) in children with AGE and dehydration, and to determine which clinical, laboratory, and treatment parameters are associated with an RVA. METHODS: The investigators performed a case control study of children aged 6 months to 6 years who presented to an urban ED with AGE and dehydration and who received IV rehydration before discharge from the ED. Dehydration was defined a priori on the basis of parameters used in prior studies. Cases were defined as those patients who had an RVA within 72 hours of an original visit for ongoing symptoms. Controls were defined as those patients who met inclusion criteria who did not have an RVA. The authors studied whether the amount of IV dextrose administered at the initial visit was related to an RVA as well as which other clinical and treatment parameters were associated with an RVA. RESULTS: A total of 56 cases and 112 controls were studied. Patients who had an RVA received significantly less IV dextrose (mean: 399 mg/kg vs. 747 mg/kg, p < 0.001) than those who did not have an RVA. Patients who received no IV dextrose had 3.9 times greater odds of having a return visit with admission than those who received some dextrose. Controlling for fluid volume, the amount of dextrose administered remained statistically significant by logistic regression; for every 500 mg/kg of IV dextrose administered, the patient was 1.9 times less likely to have an RVA. Patients with length of symptoms less than or equal to one day were more likely to have an RVA than were those with symptom length of two or more days. No other historical or physical exam findings or laboratory parameters (including mean serum bicarbonate) were associated with a return visit requiring admission. CONCLUSIONS: Administration of larger amounts of IV dextrose is associated with reduced return visits requiring admission in children with gastroenteritis and dehydration. |
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Authors:
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Jason A Levy; Richard G Bachur |
Publication Detail:
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Type: Journal Article Date: 2007-02-12 |
Journal Detail:
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Title: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Volume: 14 ISSN: 1553-2712 ISO Abbreviation: Acad Emerg Med Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-04-02 Completed Date: 2007-05-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9418450 Medline TA: Acad Emerg Med Country: United States |
Other Details:
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Languages: eng Pagination: 324-30 Citation Subset: IM |
Affiliation:
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Division of Emergency Medicine, Children's Hospital Boston, Harvard Medical School, Boston, MA, USA. jason.levy@childrens.harvard.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Case-Control Studies Chi-Square Distribution Child Child, Preschool Dehydration / etiology, therapy* Emergency Service, Hospital Emergency Treatment / methods* Female Fluid Therapy / methods* Gastroenteritis / complications* Glucose / therapeutic use* Humans Infant Infusions, Intravenous Male Statistics, Nonparametric Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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