Document Detail


Intravenous cholecystokinin octapeptide in pigs reduces operant responding for food, water, sucrose solution or radiant heat.
MedLine Citation:
PMID:  6306701     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of intravenous injections of 0 (Saline vehicle), 10, 20 or 40 units of CCK was studied in pigs performing operant responses for food, water, sucrose solution or radiant heat. In hungry pigs working for food, thirsty pigs responding for water, and non-deprived pigs working for sucrose, 20 and 40 units CCK produced significant dose-related decreases in response rates lasting for about 5 min. In pigs responding for 10 sec bursts of infra-red heat at an ambient temperature of 5 degrees C, 40 units CCK significantly reduced the response rate during the 5 min period following injection.
Authors:
B A Baldwin; T R Cooper; R F Parrott
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiology & behavior     Volume:  30     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  1983 Mar 
Date Detail:
Created Date:  1983-08-11     Completed Date:  1983-08-11     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  399-403     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Appetitive Behavior / drug effects*
Body Temperature Regulation / drug effects
Cholecystokinin / pharmacology*
Conditioning, Operant / drug effects*
Dose-Response Relationship, Drug
Drinking / drug effects
Eating / drug effects
Injections, Intravenous
Motivation / drug effects*
Peptide Fragments / pharmacology*
Sincalide
Swine
Taste / drug effects
Chemical
Reg. No./Substance:
0/Peptide Fragments; 25126-32-3/Sincalide; 9011-97-6/Cholecystokinin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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