| Intravenous calcium infusion as a novel preventive therapy of ovarian hyperstimulation syndrome for patients with polycystic ovarian syndrome. | |
| | |
MedLine Citation:
|
PMID: 21621772 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
OBJECTIVE: To evaluate the effectiveness of IV calcium infusion on prevention of ovarian hyperstimulation syndrome (OHSS) in patients with polycystic ovary syndrome undergoing assisted reproductive techniques cycles. DESIGN: A retrospective comparative study. SETTING: Assisted reproduction techniques centre in Turkey. PATIENT(S): Four hundred fifty-five women with high risk for OHSS. INTERVENTION(S): The patients in group I (n = 84) were administered IV calcium gluconate for prevention of OHSS, and the patients in group II (n = 371) comprised the control group, with no manipulation for prevention of OHSS and were age- and body mass index-matched with the study group. MAIN OUTCOME MEASURE(S): Ovarian hyperstimulation syndrome rate, clinical pregnancy rate. RESULT(S): Mean (±SD) ages of the women in the calcium infusion group (group I) and the control group (group II) were comparable (30.5 ± 4.3 vs. 31.4 ± 3.9, respectively). Ovarian hyperstimulation syndrome was found in 16.2% (60 patients) in group II, whereas in group I, only 3 patients (3.6%) developed OHSS. Interestingly, all the hyperstimulation cases in group I were mild, and there was no severe effect. Implantation rates were similar in both groups. Furthermore, we obtained clinical pregnancy in nearly 40.5% in group I and 28.8% in group II. The live-birth rate was 38.1% in the calcium infusion group and 24.8% in the control group. CONCLUSION(S): Intravenous calcium infusion resulted in a significantly lower rate of development of OHSS for patients with polycystic ovary syndrome and high risk of OHSS. This novel therapy may be used for prevention of OHSS effectively. |
| | |
Authors:
|
Timur Gurgan; Aygul Demirol; Suleyman Guven; Moncef Benkhalifa; Bagdagul Girgin; Tin Chiu Li |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-5-28 |
Journal Detail:
|
Title: Fertility and sterility Volume: - ISSN: 1556-5653 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-5-30 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
|
Gurgan Clinic Women Health, Infertility and IVF Center, Ankara, Turkey; Department of Obstetrics and Gynecology, Hacettepe University, Ankara, Turkey. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Quantification of the impact of endometriosis symptoms on health-related quality of life and work pr...
Next Document: Ultrasound ovarian assessments after endometrioma ablation using plasma energy.