Document Detail


Intravenous atropine relieves coronary arterial spasm and hemodynamic decompensation during recovery after exercise.
MedLine Citation:
PMID:  10928512     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 66-year-old man developed right coronary arterial spasm and hemodynamic decompensation during the early recovery phase of a treadmill exercise test. The unstable condition was corrected immediately after intravenous administration of atropine. A subsequent coronary angiographic study revealed insignificant right coronary artery stenosis. The pathophysiology of this response may be related to rapid alterations in autonomic balance during recovery after exercise. To our knowledge, this is the 1st reported case in which atropine effected immediate reversal of coronary arterial spasm and hemodynamic decompensation that were induced by exercise, rather than by pharmacologic agents. Atropine might be an effective treatment in patients who experience exercise-induced coronary arterial spasm and hemodynamic decompensation, but further investigation is warranted.
Authors:
M J Hung; C H Wang; L T Kuo; W J Cherng
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital     Volume:  27     ISSN:  0730-2347     ISO Abbreviation:  Tex Heart Inst J     Publication Date:  2000  
Date Detail:
Created Date:  2000-12-07     Completed Date:  2000-12-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  8214622     Medline TA:  Tex Heart Inst J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  212-4     Citation Subset:  IM    
Affiliation:
Department of Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Atropine / administration & dosage,  therapeutic use*
Coronary Vasospasm / drug therapy*,  physiopathology,  radionuclide imaging
Exercise / physiology*
Exercise Test
Heart / radionuclide imaging
Hemodynamics / physiology*
Humans
Injections, Intravenous
Male
Tomography, Emission-Computed, Single-Photon
Chemical
Reg. No./Substance:
51-55-8/Atropine
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Primary vascular echinococcosis: an uncommon cause of chronic iliofemoral arterial occlusion.
Next Document:  Combined percutaneous atrial septal defect occlusion and pulmonary balloon valvuloplasty in adult pa...