Document Detail

Intravenous atropine relieves coronary arterial spasm and hemodynamic decompensation during recovery after exercise.
MedLine Citation:
PMID:  10928512     Owner:  NLM     Status:  MEDLINE    
A 66-year-old man developed right coronary arterial spasm and hemodynamic decompensation during the early recovery phase of a treadmill exercise test. The unstable condition was corrected immediately after intravenous administration of atropine. A subsequent coronary angiographic study revealed insignificant right coronary artery stenosis. The pathophysiology of this response may be related to rapid alterations in autonomic balance during recovery after exercise. To our knowledge, this is the 1st reported case in which atropine effected immediate reversal of coronary arterial spasm and hemodynamic decompensation that were induced by exercise, rather than by pharmacologic agents. Atropine might be an effective treatment in patients who experience exercise-induced coronary arterial spasm and hemodynamic decompensation, but further investigation is warranted.
M J Hung; C H Wang; L T Kuo; W J Cherng
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital     Volume:  27     ISSN:  0730-2347     ISO Abbreviation:  Tex Heart Inst J     Publication Date:  2000  
Date Detail:
Created Date:  2000-12-07     Completed Date:  2000-12-07     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  8214622     Medline TA:  Tex Heart Inst J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  212-4     Citation Subset:  IM    
Department of Medicine, Chang Gung Memorial Hospital, Keelung, Taiwan.
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MeSH Terms
Atropine / administration & dosage,  therapeutic use*
Coronary Vasospasm / drug therapy*,  physiopathology,  radionuclide imaging
Exercise / physiology*
Exercise Test
Heart / radionuclide imaging
Hemodynamics / physiology*
Injections, Intravenous
Tomography, Emission-Computed, Single-Photon
Reg. No./Substance:

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