Document Detail

Intravenous alpha-1-antitrypsin replacement therapy: case report after one year of treatment.
MedLine Citation:
PMID:  9057422     Owner:  NLM     Status:  MEDLINE    
Alpha-1-antitrypsin deficiency is an autosomally inherited disease in which individuals homozygous for the disorder are prone to develop severe emphysema. We report the case of a 43 yr old man with severe deficiency and advanced emphysema and the first experience in Ireland with intravenous alpha-1-antitrypsin replacement. After 1 yr of replacement therapy we report our experience with dosage and frequency of infusion as well as pulmonary function test data before and during treatment.
A C Ward; B A Keogh
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Irish journal of medical science     Volume:  166     ISSN:  0021-1265     ISO Abbreviation:  Ir J Med Sci     Publication Date:    1997 Jan-Mar
Date Detail:
Created Date:  1997-04-14     Completed Date:  1997-04-14     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7806864     Medline TA:  Ir J Med Sci     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  7-9     Citation Subset:  IM    
Mater Misericordiae Hospital, Dublin.
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MeSH Terms
Drug Administration Schedule
Follow-Up Studies
Pulmonary Emphysema / drug therapy*,  etiology
Respiratory Function Tests
Serine Proteinase Inhibitors / administration & dosage,  therapeutic use*
alpha 1-Antitrypsin / administration & dosage,  therapeutic use*
Reg. No./Substance:
0/Serine Proteinase Inhibitors; 0/alpha 1-Antitrypsin

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