Document Detail

Intravenous Thrombolysis in Thai Patients with Acute Ischemic Stroke: Role of Aging.
MedLine Citation:
PMID:  22177929     Owner:  NLM     Status:  Publisher    
BACKGROUND: Intravenous thrombolysis is a standard treatment in eligible acute ischemic stroke (AIS) patients. However, the advisability of treating patients >80 years of age is still debated. The aim of this study was to evaluate the role of aging on the outcomes in Thai patients treated with intravenous thrombolysis. METHODS: Patients with AIS treated with intravenous recombinant tissue-plasminogen activator (rtPA) between June 2007 and November 2010 were included. The demographics and measured outcome variables were compared between patients ≤70 and >70 years of age. Patients were also classified into 4 subgroups by the age ranges: ≤60 years, 61 to 70 years, 71 to 80 years, and ≥81 years of age. RESULTS: Two hundred sixty-one patients were included. Seventeen patients (6.5%) were >80 years old. Higher mortality (20.2% vs 5.1%; P < .001) and symptomatic intracerebral hemorrhage (7.7% vs 1.2%; P = .004) were found in the patients >70 years of age when compared with younger patients, and the rate of favorable outcome was lower (38.1% vs 55.4%; P = .010). Higher mortality rates were seen with increasing age: 3%, 8%, 20%, and 21% in patients aged ≤60, 61 to 70, 71 to 80, and ≥81 years of age, respectively. CONCLUSIONS: Thai stroke patients >70 years of age may carry a higher risk of mortality when treated with intravenous rtPA compared to patients ≤70 years of age.
Pornpatr A Dharmasaroja; Sombat Muengtaweepongsa; Permphan Dharmasaroja
Related Documents :
20160409 - Blood lead level and cardiovascular risk factors among bus drivers in bangkok, thailand.
19570309 - A comparison of the hazard perception ability of matched groups of healthy drivers aged...
1285819 - Accidents in the north. some aspects on snowmobile accidents and moose-car collisions.
18032909 - To continue, modify or relinquish driving: findings from a longitudinal study of health...
11817839 - Seafarers' accidents: does age, rank or experience matter?
1856649 - Inaccuracy of height information on driver's licenses.
2837059 - Prevalence of ocular disease and blindness in a rural area in the eastern region of ice...
15676749 - The importance of heel compression in the measurement of diurnal stature variation.
12452249 - Circadian rhythm of some parameters of body composition in the elderly investigated by ...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-14
Journal Detail:
Title:  Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association     Volume:  -     ISSN:  1532-8511     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111633     Medline TA:  J Stroke Cerebrovasc Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 National Stroke Association. Published by Elsevier Inc. All rights reserved.
Division of Neurology, Department of Internal Medicine, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Development of Transdural Anastomosis After Craniotomy in a Patient With Atherothrombotic Carotid Oc...
Next Document:  Height and risk of incident intraparenchymal hemorrhage: Atherosclerosis Risk in Communities and Car...