Document Detail

Intravascular ultrasound predictors of restenosis after balloon angioplasty of the femoropopliteal artery.
MedLine Citation:
PMID:  9728429     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To determine intravascular ultrasound parameters related to restenosis following percutaneous transluminal balloon angioplasty (PTA) of the femoropopliteal artery. DESIGN: Prospective study. MATERIALS AND METHODS: Patients were studies with intravascular ultrasound before and after angiographic successful PTA (n = 114). Intravascular ultrasound cross-sections obtained with 1 cm interval in the dilated segment were analysed. A distinction was made between anatomic (duplex scanning) and clinical (Rutherford criteria) restenosis assessed within 1 month and at 6 months after PTA. RESULTS: Intravascular ultrasound predictors of 1 month anatomic outcome were lumen area stenosis after PTA, lumen area increase, plaque area decrease, and area stenosis decrease; predictor of 6 months anatomic outcome was area stenosis after PTA. Multivariate analysis revealed that area stenosis after PTA was the only independent predictor of both 1 and 6 months anatomic outcome. Intravascular ultrasound predictors of 1 month clinical outcome were the presence of hard lesion and the mean arc of hard lesion. Multivariate analysis revealed that the mean arc of hard lesion was the only independent predictor of 1 month clinical outcome. No predictors for 6 months clinical outcome were found. CONCLUSIONS: Intravascular ultrasound can elucidate parameters predictive of restonosis after PTA. The strongest intravascular ultrasound parameter predictive of anatomic restenosis was a large area stenosis after PTA.
A van der Lugt; E J Gussenhoven; G Pasterkamp; T Stijnen; J A Reekers; F G van den Berg; A V Tielbeek; J L Seelen; H Pieterman
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Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery     Volume:  16     ISSN:  1078-5884     ISO Abbreviation:  Eur J Vasc Endovasc Surg     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-09-25     Completed Date:  1998-09-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9512728     Medline TA:  Eur J Vasc Endovasc Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  110-9     Citation Subset:  IM    
University Hospital Rotterdam-Dijkzigt, Erasmus University Rotterdam, The Netherlands.
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MeSH Terms
Angioplasty, Balloon*
Arterial Occlusive Diseases / epidemiology,  therapy*,  ultrasonography*
Femoral Artery*
Follow-Up Studies
Popliteal Artery*
Predictive Value of Tests
Time Factors
Treatment Outcome
Ultrasonography, Interventional*
Comment In:
Eur J Vasc Endovasc Surg. 1999 Dec;18(6):463-5   [PMID:  10637139 ]

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