Document Detail

Intravascular ultrasound imaging of angiographically normal coronary segments in patients with coronary artery disease.
MedLine Citation:
PMID:  8122599     Owner:  NLM     Status:  MEDLINE    
Intravascular ultrasound imaging (IVUS) constitutes a new diagnostic technique that provides unique information concerning arterial wall structure and luminal dimensions. To assess the anatomic features of angiographically normal coronary arteries in patients with coronary artery disease, 25 patients (aged 61 +/- 9 years) underwent an IVUS examination before coronary angioplasty. A mechanical (20 MHz) IVUS system was used. Atherosclerotic plaques were identified by IVUS as well-defined structures of variable echodensity protruding into the coronary lumen or disrupting normal coronary wall architecture. Five (20%) patients had minor angiographic irregularities proximal to the target lesion, and all 5 had plaque on IVUS. In the remaining 20 patients the coronary segments proximal to the target lesion were angiographically normal. Of these, IVUS demonstrated the presence of plaque in 16 (80%) patients at 19 different angiographic sites (3 lipidic, 13 fibrotic, 3 calcified). Fifteen plaques had a semilunar appearance and did not disrupt luminal contour, but four clearly protruded into the coronary lumen. Six plaques were located in the left main artery, 4 in the left anterior descending artery, 4 in the left circumflex artery, 4 in the right coronary artery, and 1 in a vein graft. On quantitative angiography, luminal diameter, at sites angiographically normal but with plaque on IVUS, was 3.6 +/- 1 mm. At these sites, both minimal luminal diameter (3.5 +/- 1 mm) and maximal luminal diameter (4.3 +/- 1 mm) on IVUS correlated (r = 0.59 and r = 0.61, respectively) with angiographic measurements (p < 0.05). No complications resulted from the IVUS study.(ABSTRACT TRUNCATED AT 250 WORDS)
F Alfonso; C Macaya; J Goicolea; A Iñiguez; R Hernandez; J Zamorano; M J Perez-Vizcayne; P Zarco
Related Documents :
1024259 - Spontaneous aorta and coronary lesions in mountain mammals. i. the carpathian deer (cer...
16875309 - Preoperative extracranial carotid artery examination with ultrasonography in patients u...
9737619 - Compensatory arterial enlargement is a common pathobiologic response in early atheroscl...
20863499 - Serum uric acid levels predict the severity and morphology of coronary atherosclerosis ...
11695779 - Dosimetric effect of source centering and residual plaque for beta-emitting catheter ba...
11871929 - Association between chlamydia pneumoniae antibodies and intimal calcification in femora...
15064849 - Axillary artery injury from humeral neck fracture: a rare but disabling traumatic event.
18407609 - Ischemic colitis due to obstruction of mesenteric and splenic veins: a case report.
15756369 - Subaortic membrane in an adult patient with coronary artery disease.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American heart journal     Volume:  127     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-04-05     Completed Date:  1994-04-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  536-44     Citation Subset:  AIM; IM    
Cardiopulmonary Department, Hospital Universitario San Carlos, Madrid, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Coronary Angiography
Coronary Artery Disease / ultrasonography
Coronary Disease / ultrasonography*
Coronary Vessels / ultrasonography*
Middle Aged
Ultrasonography, Interventional* / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Usefulness of changes in exercise tolerance induced by nitroglycerin in identifying patients with sy...
Next Document:  Effects of heart rate on phasic coronary blood flow pattern and flow reserve in patients with normal...