Document Detail

Intravascular ultrasound guidance in drug-eluting stent deployment.
MedLine Citation:
PMID:  18432170     Owner:  NLM     Status:  MEDLINE    
The role of routine intravascular ultrasound (IVUS) guidance during percutaneous coronary intervention (PCI) in the bare metal stent era remains controversial. The potential to reduce revascularization was reported without impacting non-fatal myocardial infarction and death. Drug-eluting stents (DES) have realized improved clinical results in patients undergoing PCI but are not free of restenosis and are limited by thrombosis, particularly in more complex lesion types. Stent under-expansion, malposition, and incomplete lesion coverage have been identified as the key mechanisms of DES failure. The identification of these features on IVUS and their subsequent treatment may lead to improved clinical outcomes. Though a clinical benefit is intuitive, results from randomized trials are still needed to justify routine IVUS guided DES implantation. The Authors provide a review of the currently available evidence pertaining to the potential clinical benefit of IVUS guidance in DES implantation.
P Roy; R Waksman
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Minerva cardioangiologica     Volume:  56     ISSN:  0026-4725     ISO Abbreviation:  Minerva Cardioangiol     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-04-24     Completed Date:  2008-06-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400725     Medline TA:  Minerva Cardioangiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  67-77     Citation Subset:  IM    
Division of Cardiology, Washington Hospital Center, Washington, DC 20010, USA.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary / methods*
Coronary Artery Disease / therapy*,  ultrasonography*
Drug-Eluting Stents*
Evidence-Based Medicine
Myocardial Revascularization / methods
Treatment Outcome
Ultrasonography, Interventional*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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