Document Detail

Intravascular polymer material after coil embolization of a giant cerebral aneurysm.
MedLine Citation:
PMID:  19716159     Owner:  NLM     Status:  MEDLINE    
We report the case of an 87-year-old female who died after coil embolization of an intracerebral giant aneurysm. Guglielmi detachable (Boston Scientific Neurovascular, Fremont, CA) and Matrix2 coils (Boston Scientific Neurovascular, Fremont, CA) were used during the procedure to occlude the surgically untreatable left supraclinoid carotid artery aneurysm. Postprocedure imaging studies showed scattered areas of acute infarct involving multiple bilateral vascular territories. Autopsy confirmed widespread infarction due to embolized foreign material, morphologically consistent with hydrophilic polymer originating from the coated Matrix coil and Terumo glidewire (Terumo Medical, Somerset, NJ). Polymer gel is now widely used on several medical devices for interventional procedures worldwide, and we suspect that risks associated with iatrogenic embolization of this substance are underrecognized.
Rupal I Mehta; Rashi I Mehta; Michael C Fishbein; Orestes E Solis; Reza Jahan; Noriko Salamon; Harry V Vinters; William H Yong
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2009-08-27
Journal Detail:
Title:  Human pathology     Volume:  40     ISSN:  1532-8392     ISO Abbreviation:  Hum. Pathol.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-16     Completed Date:  2009-12-15     Revised Date:  2014-03-19    
Medline Journal Info:
Nlm Unique ID:  9421547     Medline TA:  Hum Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1803-7     Citation Subset:  IM    
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MeSH Terms
Aged, 80 and over
Carotid Artery Diseases / therapy
Cerebral Infarction / etiology*,  pathology
Coronary Artery Disease / complications
Embolization, Therapeutic / adverse effects*
Fatal Outcome
Heart Failure / complications
Hypertension / complications
Intracranial Aneurysm / therapy*
Peripheral Vascular Diseases / complications
Polymers / adverse effects*
Prostheses and Implants / adverse effects*
Renal Insufficiency, Chronic / complications
Grant Support
NS044378/NS/NINDS NIH HHS; P50 NS044378/NS/NINDS NIH HHS; P50 NS044378-059002/NS/NINDS NIH HHS
Reg. No./Substance:

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