Document Detail

Intravascular papillary endothelial hyperplasia arising from the upper lip.
MedLine Citation:
PMID:  12956089     Owner:  NLM     Status:  MEDLINE    
We report a rare case of intravascular papillary endothelial hyperplasia (IPEH) arising from the upper lip. Pathologically, it consisted of a few lobulated masses lined by an incomplete fibrous capsule of variable thickness which was separated from the surrounding tissue and which partially formed papillary structures bearing fibrous stalks and a single layer of endothelium. The capillary formation was poorly defined, and mitotic figures were frequently observed. Immunohistochemically, the endothelial cells were positive for factor VIII related antigen and vimentin, and many cells were positive for PCNA, not only in the solid proliferating area but also in the papillary proliferating area. This case represents IPEH with high proliferative activity.
Kenichi Matsuzaka; Yoshihiko Koike; Takashi Yakushiji; Masaki Shimono; Takashi Inoue
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Bulletin of Tokyo Dental College     Volume:  44     ISSN:  0040-8891     ISO Abbreviation:  Bull. Tokyo Dent. Coll.     Publication Date:  2003 May 
Date Detail:
Created Date:  2003-09-05     Completed Date:  2003-10-15     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7505414     Medline TA:  Bull Tokyo Dent Coll     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  55-9     Citation Subset:  D    
Department of Clinical Pathophysiology, Oral Health Science Center, Tokyo Dental College, 1-2-2 Masago, Mihama-ku, Chiba 261-8502, Japan.
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MeSH Terms
Endothelium, Vascular / pathology*
Hyperplasia / pathology
Lip / blood supply*
Proliferating Cell Nuclear Antigen / analysis
Vascular Diseases / pathology*
Vimentin / analysis
von Willebrand Factor / analysis
Reg. No./Substance:
0/Proliferating Cell Nuclear Antigen; 0/Vimentin; 0/von Willebrand Factor
Erratum In:
Bull Tokyo Dent Coll. 2003 Aug;44(3):177

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