Document Detail

Intravascular papillary endothelial hyperplasia arising within a posteroinferior cerebellar artery aneurysm: case report and review of the literature.
MedLine Citation:
PMID:  11014437     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE AND IMPORTANCE: Intravascular papillary endothelial hyperplasia (IPEH) is an atypical proliferation of endothelium that results in abnormal organization for thrombus formation. Intracranial IPEH is a rare entity and has not been reported to arise from within an intracranial aneurysm. Furthermore, the elapsed time during which acquired intracranial IPEH develops has not been previously documented. CLINICAL PRESENTATION: In this case report, a patient with facial and neck pain was noted to have an enhancing mass lesion lateral to the medulla in magnetic resonance imaging scans. Angiography revealed a vascular mass adjacent to the posteroinferior cerebellar artery. Normal magnetic resonance imaging and magnetic resonance angiographic findings had been obtained for the patient 29 months earlier. INTERVENTION: During surgery, a thrombosed, 2.5-cm, posteroinferior cerebellar artery aneurysm was resected and noted to contain florid IPEH. There has been no evidence of recurrence in 1 year of follow-up monitoring. A literature search revealed 13 cases of intracranial IPEH, in which recurrence was observed for incompletely resected lesions. CONCLUSION: IPEH can develop in a relatively short time, can present as a hypervascular mass lesion or within an intracranial aneurysm, and should be completely resected to prevent recurrence.
W S Lesley; W J Kupsky; M Guthikonda
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Neurosurgery     Volume:  47     ISSN:  0148-396X     ISO Abbreviation:  Neurosurgery     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2001-01-08     Completed Date:  2001-01-25     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7802914     Medline TA:  Neurosurgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  961-5; discussion 966     Citation Subset:  IM    
Department of Radiology, Harper Hospital/Detroit Medical Center and Wayne State University, Michigan, USA.
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MeSH Terms
Angiography, Digital Subtraction
Cerebellum / blood supply*
Cerebral Angiography
Endothelium, Vascular / pathology*
Intracranial Aneurysm / diagnosis,  pathology*
Magnetic Resonance Imaging
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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