Document Detail

Intravascular leiomyomatosis and benign metastasizing leiomyoma: an unusual case.
MedLine Citation:
PMID:  16803546     Owner:  NLM     Status:  MEDLINE    
Benign metastasizing leiomyoma (BML) and intravascular leiomyomatosis (IVL) are rare variants of uterine leiomyomas. In our search of available literature, there have been only two reports of these conditions occurring in the same patient. We report a case of a 42-year-old female presenting with a left L4 nerve root lesion, left paravesical lesion, left ovarian cyst, multiple pulmonary metastases, and an intracaval lesion. Histology confirmed these to be leiomyomata strongly positive for estrogen receptors. Treatment included surgery, in two stages, to remove the L4 nerve root, left paravesical lesion, intracaval lesion, and a single pulmonary nodule. The remaining tumor was treated with a gonadotrophin-releasing hormone agonist, resulting in significant reductions in tumor size. It was concluded that the lesions in the lungs were an example of BML arising from the initial diagnosis of uterine leiomyoma, and the caval lesion was an IVL. Long-term follow-up is recommended, and familiarity with rare forms of benign smooth muscle uterine tumors is essential in avoiding misdiagnosis and overtreatment.
S Arif; R Ganesan; D Spooner
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of gynecological cancer : official journal of the International Gynecological Cancer Society     Volume:  16     ISSN:  1048-891X     ISO Abbreviation:  Int. J. Gynecol. Cancer     Publication Date:    2006 May-Jun
Date Detail:
Created Date:  2006-06-28     Completed Date:  2007-02-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9111626     Medline TA:  Int J Gynecol Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1448-50     Citation Subset:  IM    
Department of Oncology, Queen Elizabeth Hospital, Metchley Lane, Edgbaston, Birmingham B15 2TH, UK.
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MeSH Terms
Leiomyoma / diagnosis*
Leiomyomatosis / complications,  diagnosis*
Lung Neoplasms / radiography,  secondary
Magnetic Resonance Imaging
Uterine Neoplasms / pathology*,  radiography
Vascular Neoplasms / diagnosis*,  radiography

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